A content-based dataset recommendation system for researchers-a case study on Gene Expression Omnibus (GEO) repository

A content-based dataset recommendation system for researchers-a case study on Gene Expression Omnibus (GEO) repository

It is a rising development amongst researchers to make their knowledge publicly obtainable for experimental reproducibility and knowledge reusability. Sharing knowledge with fellow researchers helps in growing the visibility of the work. On the opposite hand, there are researchers who’re inhibited by the shortage of knowledge sources. To overcome this problem, many repositories and data bases have been established to this point to ease knowledge sharing. Further, prior to now 20 years, there was an exponential enhance within the variety of datasets added to those dataset repositories.

However, most of those repositories are domain-specific, and none of them can advocate datasets to researchers/customers. Naturally, it’s difficult for a researcher to maintain monitor of all of the related repositories for potential use. Thus, a dataset recommender system that recommends datasets to a researcher primarily based on earlier publications can improve their productiveness and expedite additional analysis. The potential to focus onto subnetworks, a number of visualizations and simulation choices will allow the AMD analysis neighborhood to computationally mannequin subnetworks or to check experimentally new hypotheses arising from connectivities in the AMD pathway map.

This work adopts an info retrieval (IR) paradigm for dataset recommendation. We hypothesize that two elementary variations exist between dataset recommendation and PubMed-style biomedical IR past the corpus. First, as an alternative of key phrases, the question is the researcher, embodied by his or her publications. Second, to filter the related datasets from non-relevant ones, researchers are higher represented by a set of pursuits, versus your entire physique of their analysis. This second strategy is applied utilizing a non-parametric clustering method.

These clusters are used to advocate datasets for every researcher utilizing the cosine similarity between the vector representations of publication clusters and datasets. The most normalized discounted cumulative acquire at 10 (NDCG@10), precision at 10 (p@10) partial and p@10 strict of 0.89, 0.78 and 0.61, respectively, have been obtained utilizing the proposed methodology after handbook analysis by 5 researchers. As per one of the best of our data, that is the primary study of its variety on content-based dataset recommendation.

Cancer PRSweb: An Online Repository with Polygenic Risk Scores for Major Cancer Traits and Their Evaluation in Two Independent Biobanks

To facilitate scientific collaboration on polygenic threat scores (PRSs) analysis, we created an intensive PRS on-line repository for 35 frequent most cancers traits integrating freely obtainable genome-wide affiliation research (GWASs) abstract statistics from three sources: printed GWASs, the NHGRI-EBI GWAS Catalog, and UK Biobank-based GWASs. Our framework condenses these abstract statistics into PRSs utilizing varied approaches comparable to linkage disequilibrium pruning/p worth thresholding (mounted or data-adaptively optimized thresholds) and penalized, genome-wide impact dimension weighting.
We evaluated the PRSs in two biobanks: the Michigan Genomics Initiative (MGI), a longitudinal biorepository effort at Michigan Medicine, and the population-based UK Biobank (UKB). For every PRS assemble, we offer measures on predictive efficiency and discrimination. Besides PRS analysis, the Cancer-PRSweb platform options assemble downloads and phenome-wide PRS affiliation study outcomes (PRS-PheWAS) for predictive PRSs. We count on this built-in platform to speed up PRS-related most cancers analysis.
This multicenter, double-blind, randomized, placebo-controlled study enrolled sufferers ≥ 18 years with lively SLE and reasonable to extreme rash and/or arthritis regardless of steady glucocorticoid doses (7.5-30 mg/day prednisone equal) and antimalarials for ≥ Four weeks and/or immunosuppressants for ≥ eight weeks earlier than screening. Stable glucocorticoid doses have been required by way of week 16 with optionally available taper from weeks 16 to 24.
Patients have been randomized (1:1) to 80 U RCI subcutaneously or placebo each different day to week 4, then twice weekly to week 24. Endpoints included the proportion of SLE Responder Index (SRI)-Four responders at week 16; modifications from baseline to week 16 in 28 Swollen Joint Count/Tender Joint Count (28 SJC/TJC) and Cutaneous Lupus Erythematosus Disease Area and Severity Index (CLASI)-Activity rating; and modifications from baseline to week 24 in inflammatory cytokines. Safety was assessed by antagonistic occasions.
A content-based dataset recommendation system for researchers-a case study on Gene Expression Omnibus (GEO) repository

Advancing COVID-19 differentiation with a sturdy preprocessing and integration of multi-institutional open-repository laptop tomography datasets for deep studying evaluation

The coronavirus pandemic and its unprecedented penalties globally has spurred the curiosity of the synthetic intelligence analysis neighborhood. A plethora of printed research have investigated the position of imaging comparable to chest X-rays and laptop tomography in coronavirus illness 2019 (COVID-19) automated analysis. Οpen repositories of medical imaging knowledge can play a big position by selling cooperation amongst institutes in a world-wide scale. However, they might induce limitations associated to variable knowledge high quality and intrinsic variations because of the huge number of scanner distributors and imaging parameters.

In this study, a state-of-the-art customized U-Net mannequin is offered with a cube similarity coefficient efficiency of 99.6% together with a switch studying VGG-19 primarily based mannequin for COVID-19 versus pneumonia differentiation exhibiting an space underneath curve of 96.1%. The above was considerably improved over the baseline mannequin skilled with no segmentation in chosen tomographic slices of the identical dataset. The offered study highlights the significance of a sturdy preprocessing protocol for picture evaluation inside a heterogeneous imaging dataset and assesses the potential diagnostic worth of the offered COVID-19 mannequin by evaluating its efficiency to the state-of-the-art. Health-related knowledge is saved in various repositories which can be managed and managed by completely different entities.

Chicken IgY

E61I020 100ug
EUR 343

Chicken IgY

31-AC25 50 mg
EUR 270
Description: Purified Chicken IgY

Rat IgG-Biotin conjugate (isotype control) (Isotype control)

20005-B 100 ug
EUR 164

Rat IgG-FITC conjugate (isotype control) (Isotype control)

20005-F 100 ug
EUR 164

Rat IgG-HRP conjugate (isotype control) (Isotype control)

20005-HP 100 ug
EUR 164

Rat IgG-PE conjugate (isotype control) (Isotype control)

20005-PE 25 tests
EUR 202

Rabbit Isotype Control

abx200646-100ug 100 ug
EUR 328

Rabbit Isotype Control

IMN-001 100 µg
EUR 199.5

Chicken IgY Protein

abx060688-50mg 50 mg
EUR 551

Chicken IgY Protein

abx060689-10ml 10 ml
EUR 495

Chicken IgY Protein

abx061434-1g 1 g
EUR 676

Chicken IgY (Unconjugated)

LF-SA8052 5 mg
EUR 181
Description: Normal chicken yolk

Chicken IgY (Unconjugated)

LF-SA8052A 10 mg
EUR 296
Description: Normal chicken yolk

Chicken IgG unlabeled (isotype control, non-immune), purified

20010-1 1 mg
EUR 141

Custom purification of IgY from up to 6 egg yolks

IGY-1 1
EUR 651

Custom purification of IgY from up to 12 egg yolks

IGY-2 1
EUR 895

Positive control tissue section for each antibody; Based on availability INQUIRE

Control-Slides Set of 5
EUR 176

Chicken IgG-Biotin conjugate (isotype control, non-immune), purified

20010-1-B 0.5 mg
EUR 225

Chicken IgG-FITC conjugate (isotype control, non-immune), purified

20010-1-F 0.5 mg
EUR 225

Chicken IgG-HRP conjugate (isotype control, non-immune), purified

20010-1-HP 0.5 mg
EUR 225

Chicken IgM-Biotin conjugate (isotype control, non-immune) purified

20010-2-1-b 0.1 mg
EUR 225

Chicken IgG-Fc unlabeled (isotype control, non-immune), purified

20010-3-UL 0.1 mg
EUR 202

Chicken IgG Fab fragment (isotype control, non-immune), purified

20010-Fab-1 0.5 mg
EUR 225

Rabbit IgG Isotype Control

abx125003-100ul 100 ul
EUR 203

Mouse IgM Isotype Control

abx020500-02mg 0.2 mg
EUR 439

Rat IgG2a Isotype Control

11-168-C025 0.025 mg
EUR 87

Rat IgG2b Isotype Control

11-169-C025 0.025 mg
EUR 87

Mouse IgG1 Isotype Control

abx405007-01mg 0.1 mg
EUR 411

Mouse IgG1 Isotype Control

abx405009-05mg 0.5 mg
EUR 690

Mouse IgG1 Isotype Control

abx405012-1mg 1 mg
EUR 1080

Mouse IgG2a Isotype Control

abx405013-100tests 100 tests
EUR 411

Mouse IgG2a Isotype Control

abx405015-05mg 0.5 mg
EUR 690

Mouse IgG2a Isotype Control

abx405018-1mg 1 mg
EUR 1107

Rat IgG1 Isotype Control

abx405020-05mg 0.5 mg
EUR 384

Rat IgG2a Isotype Control

abx405022-1ml 1 ml
EUR 300

Rat IgG2a Isotype Control

abx405024-05mg 0.5 mg
EUR 384

Rat IgG2a Isotype Control

abx405027-1mg 1 mg
EUR 565

Rat IgG2c Isotype Control

abx405034-025mg 0.25 mg
EUR 537

Mouse IgG3 Isotype Control

abx405035-01mg 0.1 mg
EUR 411

Rat IgG1 Isotype Control

abx405039-05mg 0.5 mg
EUR 384

Rat IgG1 Isotype Control

20-abx405041
  • EUR 300.00
  • EUR 439.00
  • 0.1 mg
  • 1 mg

Rat IgG2a Isotype Control

abx405045-05mg 0.5 mg
EUR 384

Rat IgG2a Isotype Control

20-abx405047
  • EUR 300.00
  • EUR 439.00
  • 0.1 mg
  • 1 mg

Rat IgG2b Isotype Control

abx405051-05mg 0.5 mg
EUR 384

Rat IgG2b Isotype Control

20-abx405053
  • EUR 300.00
  • EUR 439.00
  • 0.1 mg
  • 1 mg

Mouse IgG2b Isotype Control

abx405056-100tests 100 tests
EUR 411

Mouse IgG2b Isotype Control

abx405061-1mg 1 mg
EUR 1080

Mouse IgM Isotype Control

abx405062-100tests 100 tests
EUR 411

Mouse IgG1 Isotype Control

abx405064-100tests 100 tests
EUR 411

Mouse IgG1 Isotype Control

abx405067-05mg 0.5 mg
EUR 829

Mouse IgG2a Isotype Control

abx405070-100tests 100 tests
EUR 411

Mouse IgG2a Isotype Control

abx405073-05mg 0.5 mg
EUR 829

Mouse IgG1 Isotype Control

abx200564-100ug 100 ug
EUR 314

Mouse IgG2a Isotype Control

abx200572-100ug 100 ug
EUR 314

Mouse IgG2b Isotype Control

abx200580-100ug 100 ug
EUR 314

Mouse IgG3 Isotype Control

abx200587-100ug 100 ug
EUR 356

Mouse IgM Isotype Control

abx200594-100ug 100 ug
EUR 314

Rat IgG2a Isotype Control

abx200644-500ug 500 ug
EUR 481

Rabbit Isotype Control (FITC)

abx200647-100test 100 test
EUR 328

Rabbit Isotype Control (PE)

abx200648-100test 100 test
EUR 328

Mouse IgG1 Isotype Control

abx139001-01mg 0.1 mg
EUR 314

Mouse IgG1 Isotype Control

abx139002-01mg 0.1 mg
EUR 314

Mouse IgM Isotype Control

abx139003-01mg 0.1 mg
EUR 314

Mouse IgG2a Isotype Control

abx139004-01mg 0.1 mg
EUR 314

Mouse IgG1 Isotype Control

abx139008-01mg 0.1 mg
EUR 314

Mouse IgG3 Isotype Control

abx139010-01mg 0.1 mg
EUR 314

Mouse IgG2a Isotype Control

abx139005-01mg 0.1 mg
EUR 314

Mouse IgG2b Isotype Control

abx139006-01mg 0.1 mg
EUR 314

Mouse IgG2a Isotype Control

abx139009-01mg 0.1 mg
EUR 314

Mouse IgG2b Isotype Control

abx139011-01mg 0.1 mg
EUR 314

Rat IgG1 Isotype Control

RIGG1A-100 100 µg
EUR 545.04

Rat IgG1 Isotype Control

RIGG1A-25 25 µg
EUR 268.4

Rat IgG1 Isotype Control

RIGG1F-50 50 µg
EUR 297.52

Rat IgG1 Isotype Control

RIGG1F-500 500 µg
EUR 879.92

Rat IgG1 Isotype Control

RIGG1PE-100 100 µg
EUR 530.48

Rat IgG1 Isotype Control

RIGG1PE-25 25 µg
EUR 253.84

Rat IgG1 Isotype Control

RIGG1PP5.5-100 100 µg
EUR 588.72

Rat IgG1 Isotype Control

RIGG1PP5.5-25 25 µg
EUR 268.4

Rat IgG1 Isotype Control

RIGG1PU-50 50 µg
EUR 181.04

Rat IgG1 Isotype Control

RIGG1PU-500 500 µg
EUR 399.44

Rat IgG2a Isotype Control

RIGG2AA-100 100 µg
EUR 312.08

Rat IgG2a Isotype Control

RIGG2AA-25 25 µg
EUR 181.04

Rat IgG2a Isotype Control

RIGG2AB-200 200 µg
EUR 457.68

Rat IgG2a Isotype Control

RIGG2AB-50 50 µg
EUR 224.72

Rat IgG2a Isotype Control

RIGG2AF-200 200 µg
EUR 312.08

Rat IgG2a Isotype Control

RIGG2AF-50 50 µg
EUR 166.48

Rat IgG2a Isotype Control

RIGG2APE-100 100 µg
EUR 282.96

Rat IgG2a Isotype Control

RIGG2APE-25 25 µg
EUR 166.48

Rat IgG2a Isotype Control

RIGG2APP-100 100 µg
EUR 574.16

Rat IgG2a Isotype Control

RIGG2APP-25 25 µg
EUR 268.4

Rat IgG2a Isotype Control

RIGG2APP5.5-100 100 µg
EUR 646.96

Rat IgG2a Isotype Control

RIGG2APP5.5-25 25 µg
EUR 282.96

Rat IgG2a Isotype Control

RIGG2APU-50 50 µg
EUR 181.04

Rat IgG2a Isotype Control

RIGG2APU-500 500 µg
EUR 399.44

Rat IgG2b Isotype Control

RIGG2BA-100 100 µg
EUR 326.64

Rat IgG2b Isotype Control

RIGG2BA-25 25 µg
EUR 166.48

Rat IgG2b Isotype Control

RIGG2BB-200 200 µg
EUR 457.68

Rat IgG2b Isotype Control

RIGG2BB-50 50 µg
EUR 224.72

Rat IgG2b Isotype Control

RIGG2BF-200 200 µg
EUR 472.24

Rat IgG2b Isotype Control

RIGG2BF-50 50 µg
EUR 151.92

Rat IgG2b Isotype Control

RIGG2BPE-100 100 µg
EUR 268.4

Rat IgG2b Isotype Control

RIGG2BPE-25 25 µg
EUR 151.92

Rat IgG2b Isotype Control

RIGG2BPP-100 100 µg
EUR 574.16

Rat IgG2b Isotype Control

RIGG2BPP-25 25 µg
EUR 268.4

Rat IgG2b Isotype Control

RIGG2BPP5.5-100 100 µg
EUR 515.92

Rat IgG2b Isotype Control

RIGG2BPP5.5-25 25 µg
EUR 282.96

Rat IgG2b Isotype Control

RIGG2BPU-50 50 µg
EUR 122.8

Rat IgG2b Isotype Control

RIGG2BPU-500 500 µg
EUR 370.32

Rat IgG2c Isotype Control

RIGG2CA-25 25 µg
EUR 253.84

Rat IgG2c Isotype Control

RIGG2CB-50 50 µg
EUR 224.72

Rat IgG2c Isotype Control

RIGG2CF-50 50 µg
EUR 253.84

Rat IgG2c Isotype Control

RIGG2CPE-25 25 µg
EUR 239.28

Rat IgG2c Isotype Control

RIGG2CPP5.5-25 25 µg
EUR 282.96

Rat IgG2c Isotype Control

RIGG2CPU-50 50 µg
EUR 181.04

Rat IgG2c Isotype Control

RIGG2CPU-500 500 µg
EUR 399.44

Rat IgM Isotype Control

RIGMA-100 100 µg
EUR 705.2

Rat IgM Isotype Control

RIGMB-200 200 µg
EUR 778

Rat IgM Isotype Control

RIGMB-50 50 µg
EUR 253.84

Rat IgM Isotype Control

RIGMF-200 200 µg
EUR 778

Rat IgM Isotype Control

RIGMF-50 50 µg
EUR 253.84

Rat IgM Isotype Control

RIGMPE-100 100 µg
EUR 457.68

Rat IgM Isotype Control

RIGMPE-25 25 µg
EUR 239.28

Rat IgM Isotype Control

RIGMPP5.5-25 25 µg
EUR 355.76

Rat IgM Isotype Control

RIGMPU-50 50 µg
EUR 181.04

Rat IgM Isotype Control

RIGMPU-500 500 µg
EUR 399.44

Rabbit IgG Isotype Control

IC001-100ul 100ul
EUR 122

Mouse IgG Isotype Control

IC002-100ul 100ul
EUR 122

IgG Isotype Control antibody

10R-6524 50 ug
EUR 133
Description: Armenian Hamster monoclonal IgG Isotype Control antibody

IgG Isotype Control antibody

10R-6525 50 ug
EUR 133
Description: Syrian Hamster monoclonal IgG Isotype Control antibody

Mouse IgG2a Isotype Control

10R-I117d 1 mg
EUR 553
Description: Purified Mouse IgG2a Isotype Control

Rat IgG Isotype Control

31-AR15 10 mg
EUR 220
Description: Purified Rat IgG Isotype Control

Rat IgG2b Isotype Control

31R-IC001 500 ug
EUR 241
Description: Purified Rat IgG2b Isotype Control

Rabbit anti Chicken IgY

E61I0201 100ug
EUR 343

Anti-Chicken IgY antibody

STJ16100614 100 µg
EUR 813

Anti-Chicken IgY antibody

STJ16100615 50 µg
EUR 645

Anti-Chicken IgY antibody

STJ16101246 1 mg
EUR 191

Anti-Chicken IgY antibody

STJ16101247 1.2 mg
EUR 229

Anti-Chicken IgY antibody

STJ16101248 1.2 mg
EUR 282

Anti-Chicken IgY antibody

STJ16101363 1 mg
EUR 191

Anti-Chicken IgY antibody

STJ16101364 1.2 mg
EUR 229

Anti-Chicken IgY antibody

STJ16101365 1.2 mg
EUR 282

Chicken IgY ELISA Kit

E-30Y 1 x 96 well plate
EUR 395

Rabbit anti Chicken IgY

20-B9093R000-R0 5 ml
EUR 138
Description: Rabbit anti Chicken IgY antibody

Chicken IgY precipitation reagent

85R-1010 4 ml
EUR 554
Description: Chicken IgY precipitation reagent for use in immunoassays

Chicken IgY (Non Immune)

31R-1052 1 ml
EUR 148
Description: Purified Chicken non immune IgY

Donkey IgG (Control, non-immune, isotype control)

20028-1 1 mg
EUR 164

Chicken IgG-Fc-Biotin conjugate (isotype control, non-immune), purified

20010-3-B 0.1 mg
EUR 225

Chicken IgG-Fc-FITC conjugate (isotype control, non-immune), purified

20010-3-F 0.1 mg
EUR 225

Chicken IgG-Fc-HRP conjugate (isotype control, non-immune), purified

20010-3-HP 0.1 mg
EUR 225

Mouse IgG1 Isotype Control PerCP

PC-632-C025 0.025 mg
EUR 136

Mouse IgG1 Isotype Control PerCP

PC-632-C100 0.1 mg
EUR 231

Mouse IgG2b Isotype Control PerCP

PC-692-C025 0.025 mg
EUR 122

Mouse IgG2b Isotype Control PerCP

PC-692-C100 0.1 mg
EUR 204

Mouse IgG2a Isotype Control PerCP

PC-724-C025 0.025 mg
EUR 122

Mouse IgG2a Isotype Control PerCP

PC-724-C100 0.1 mg
EUR 204

Mouse IgG1 Isotype Control APC

1A-632-C025 0.025 mg
EUR 122

Mouse IgG1 Isotype Control APC

1A-632-C100 0.1 mg
EUR 204

Mouse IgG2b Isotype Control APC

1A-692-C025 0.025 mg
EUR 122

Mouse IgG2b Isotype Control APC

1A-692-C100 0.1 mg
EUR 204

Mouse IgG2a Isotype Control APC

1A-724-C025 0.025 mg
EUR 122

For occasion, Electronic Health Records are normally administered by governments. Electronic Medical Records are sometimes managed by well being care suppliers, whereas Personal Health Records are managed straight by sufferers. Recently, Blockchain-based well being report programs largely regulated by know-how have emerged as one other sort of repository. Repositories for storing well being knowledge differ from each other primarily based on price, stage of safety and high quality of efficiency. Not solely has the kind of repositories elevated lately, however the quantum of well being knowledge to be saved has elevated.